产品货号：
Z27057
中文名称：
SMAD2抗体
英文名称：
Anti-SMAD2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SMAD2 Antibody |
| 指标别名 | hMAD 2;hSMAD2;JV18;JV18 1;MAD homolog 2;Mad related protein 2;MADH2;MADR2;Mothers against DPP homolog 2;SMAD 2;SMAD family member 2;SMAD2 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC |
| 基因名称 | SMAD2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human Smad2(94-112aa DQWDTTGLYSFSEQTRSLD),identical to the related rat and mouse sequences. |
| 实际分子量 | 58KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Smad2(Mothers against decapentaplegic homolog 2),also known as MADR2,MADH2,SMAD family member 2 or SMAD2,is a protein that in humans is encoded by the SMAD2 gene.MAD homolog 2 belongs to the SMAD,a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic'(Mad) and the C.elegans gene Sma.Eppert et al.(1996) mapped the MADR2 gene close to DPC4 at 18q21,a region which is frequently deleted in colorectal cancers.Riggins et al.(1996) mapped the human MADH2 gene to 18q21.Nakao et al.(1997) refined the localization of the SMAD2 gene to 18q21.1,approximately 3 Mb proximal to DPC4,by fluorescence in situ hybridization.SMAD2 mediates the signal of the transforming growth factor(TGF)-beta,and thus regulates multiple cellular processes,such as cell proliferation,apoptosis,and differentiation.This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation(SARA) protein.In response to TGF-beta signal,this protein is phosphorylated by the TGF-beta receptors. |
| Uniprot ID | Q15796 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | SMAD family member 2 |
| 蛋白名全称 | Mothers against decapentaplegic homolog 2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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